Staff Mass Spectrometrist

You operate and maintain the mass spectrometry infrastructure, including Orbitrap Astral instruments and supporting LC systems, ensuring consistently high performance. • Coordination, preparation, and processing of biological samples for stable isotope tracing, metabolomics, epitranscriptomics, and other MS-omics analyses - including low-input and single-cell samples - are part of your responsibilities. • You support the implementation of automated sample preparation pipelines to increase throughput and improve reproducibility. • Hands-on guidance and training of students and postdocs in the use of the instruments is an important part of your role. • You actively contribute to the development and optimization of LC-MS methods for metabolite quantification, isotope enrichment, lipid profiling, and modified nucleotides. • Routine instrument calibration, troubleshooting, and preventive maintenance are carried out by you independently. • You support data acquisition as well as initial QC and processing pipelines. • You perform MS data processing and analysis across applications and collaborative projects, ensuring high data quality and consistency. • You manage MS data across projects to ensure traceability, organization, and -reproducibility. • You also help manage consumables, sample logistics, and platform documentation.

Expert (MSc or PhD) in analytical chemistry, biochemistry, or a related field • Solid practical experience with LC-MS/MS - ideally on Orbitrap-based instruments • Background in stable isotope tracing and/or metabolomics in a biological setting is strongly preferred • Interest in or experience with laboratory automation - liquid handling, automated sample prep, or scripted workflows • Curiosity about emerging technologies, particularly single-cell mass spectrometry, is a genuine plus • Methodical, detail-oriented, and comfortable troubleshooting complex instrument issues • Able to work independently and communicate clearly with researchers at all levels • Experience in a core facility, CRO, or research lab environment is valued • English required; German is a plus